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Motif elucidation in ChIP-seq datasets with a knockout control

SUMMARY: Chromatin immunoprecipitation-sequencing is widely used to find transcription factor binding sites, but suffers from various sources of noise. Knocking out the target factor mitigates noise by acting as a negative control. Paired wild-type and knockout (KO) experiments can generate improved...

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Detalles Bibliográficos
Autores principales:	Denisko, Danielle, Viner, Coby, Hoffman, Michael M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074035/ https://www.ncbi.nlm.nih.gov/pubmed/37033469 http://dx.doi.org/10.1093/bioadv/vbad031

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