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Transferrin Receptor‐Mediated Iron Uptake Promotes Colon Tumorigenesis

Transferrin receptor (TFRC) is the major mediator for iron entry into a cell. Under excessive iron conditions, TFRC is expected to be reduced to lower iron uptake and toxicity. However, the mechanism whereby TFRC expression is maintained at high levels in iron‐enriched cancer cells and the contribut...

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Detalles Bibliográficos
Autores principales: Kim, Hyeoncheol, Villareal, Luke B, Liu, Zhaoli, Haneef, Mohammad, Falcon, Daniel M, Martin, David R, Lee, Ho‐Joon, Dame, Michael K, Attili, Durga, Chen, Ying, Varani, James, Spence, Jason R., Kovbasnjuk, Olga, Colacino, Justin A, Lyssiotis, Costas A., Lin, Henry C, Shah, Yatrik M, Xue, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074045/
https://www.ncbi.nlm.nih.gov/pubmed/36703617
http://dx.doi.org/10.1002/advs.202207693