An IL‐12‐Based Nanocytokine Safely Potentiates Anticancer Immunity through Spatiotemporal Control of Inflammation to Eradicate Advanced Cold Tumors

Treatment of immunologically cold tumors is a major challenge for immune checkpoint inhibitors (ICIs). Interleukin 12 (IL‐12) can invigorate ICIs against cold tumors by establishing a robust antitumor immunity. However, its toxicity and systemic induction of counteracting immunosuppressive signals h...

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Detalles Bibliográficos
Autores principales: Chen, Pengwen, Yang, Wenqian, Nagaoka, Koji, Huang, George Lo, Miyazaki, Takuya, Hong, Taehun, Li, Shangwei, Igarashi, Kazunori, Takeda, Kazuyoshi, Kakimi, Kazuhiro, Kataoka, Kazunori, Cabral, Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074049/
https://www.ncbi.nlm.nih.gov/pubmed/36739605
http://dx.doi.org/10.1002/advs.202205139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074049/
https://www.ncbi.nlm.nih.gov/pubmed/36739605
http://dx.doi.org/10.1002/advs.202205139

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