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Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice

Interferon‐induced transmembrane protein 3 (IFITM3) is an antiviral protein that alters cell membranes to block fusion of viruses. Conflicting reports identified opposing effects of IFITM3 on SARS‐CoV‐2 infection of cells, and its impact on viral pathogenesis in vivo remains unclear. Here, we show t...

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Detalles Bibliográficos
Autores principales: Kenney, Adam D, Zani, Ashley, Kawahara, Jeffrey, Eddy, Adrian C, Wang, Xiao‐Liang, Mahesh, KC, Lu, Mijia, Thomas, Jeronay, Kohlmeier, Jacob E, Suthar, Mehul S, Hemann, Emily A, Li, Jianrong, Peeples, Mark E, Hall‐Stoodley, Luanne, Forero, Adriana, Cai, Chuanxi, Ma, Jianjie, Yount, Jacob S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074051/
https://www.ncbi.nlm.nih.gov/pubmed/36880581
http://dx.doi.org/10.15252/embr.202256660