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APC/C‐dependent degradation of Spd2 regulates centrosome asymmetry in Drosophila neural stem cells

A functional centrosome is vital for the development and physiology of animals. Among numerous regulatory mechanisms of the centrosome, ubiquitin‐mediated proteolysis is known to be critical for the precise regulation of centriole duplication. However, its significance beyond centrosome copy number...

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Detalles Bibliográficos
Autores principales: Meghini, Francesco, Martins, Torcato, Zhang, Qian, Loyer, Nicolas, Trickey, Michelle, Abula, Yusanjiang, Yamano, Hiroyuki, Januschke, Jens, Kimata, Yuu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074082/
https://www.ncbi.nlm.nih.gov/pubmed/36852890
http://dx.doi.org/10.15252/embr.202255607