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Visible‐Light‐Activated Molecular Machines Kill Fungi by Necrosis Following Mitochondrial Dysfunction and Calcium Overload

Invasive fungal infections are a growing public health threat. As fungi become increasingly resistant to existing drugs, new antifungals are urgently needed. Here, it is reported that 405‐nm‐visible‐light‐activated synthetic molecular machines (MMs) eliminate planktonic and biofilm fungal population...

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Detalles Bibliográficos
Autores principales: Santos, Ana L., Beckham, Jacob L., Liu, Dongdong, Li, Gang, van Venrooy, Alexis, Oliver, Antonio, Tegos, George P., Tour, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074111/
https://www.ncbi.nlm.nih.gov/pubmed/36715588
http://dx.doi.org/10.1002/advs.202205781