Pericyte stem cells induce Ly6G (+) cell accumulation and immunotherapy resistance in pancreatic cancer

We report the identification of a cell population that shares pericyte, stromal and stemness features, does not harbor the Kras (G12D) mutation and drives tumoral growth in vitro and in vivo. We term these cells pericyte stem cells (PeSCs) and define them as CD45(−)EPCAM(−)CD29(+)CD106(+)CD24(+)CD44...

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Detalles Bibliográficos
Autores principales: Wu, Zhichong, Thierry, Kevin, Bachy, Sophie, Zhang, Xinyi, Gamradt, Pia, Hernandez‐Vargas, Hector, Mikaelian, Ivan, Tonon, Laurie, Pommier, Roxanne, Zhao, Yajie, Bertolino, Philippe, Hennino, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074138/
https://www.ncbi.nlm.nih.gov/pubmed/36802267
http://dx.doi.org/10.15252/embr.202256524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074138/
https://www.ncbi.nlm.nih.gov/pubmed/36802267
http://dx.doi.org/10.15252/embr.202256524

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