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Pericyte stem cells induce Ly6G (+) cell accumulation and immunotherapy resistance in pancreatic cancer
We report the identification of a cell population that shares pericyte, stromal and stemness features, does not harbor the Kras (G12D) mutation and drives tumoral growth in vitro and in vivo. We term these cells pericyte stem cells (PeSCs) and define them as CD45(−)EPCAM(−)CD29(+)CD106(+)CD24(+)CD44...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074138/ https://www.ncbi.nlm.nih.gov/pubmed/36802267 http://dx.doi.org/10.15252/embr.202256524 |