Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes

The eukaryotic BBSome is a transport complex within cilia and assembled by chaperonin-like BBS proteins. Recent work indicates nuclear functions for BBS proteins in mammals, but it is unclear how common these are in extant proteins or when they evolved. We screened for BBS orthologues across a diver...

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Detalles Bibliográficos
Autores principales: Ewerling, Alexander, Maissl, Vanessa, Wickstead, Bill, May-Simera, Helen Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074162/
https://www.ncbi.nlm.nih.gov/pubmed/37034981
http://dx.doi.org/10.1016/j.isci.2023.106410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074162/
https://www.ncbi.nlm.nih.gov/pubmed/37034981
http://dx.doi.org/10.1016/j.isci.2023.106410

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