Cargando…
Neofunctionalization of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
The eukaryotic BBSome is a transport complex within cilia and assembled by chaperonin-like BBS proteins. Recent work indicates nuclear functions for BBS proteins in mammals, but it is unclear how common these are in extant proteins or when they evolved. We screened for BBS orthologues across a diver...
Autores principales: | Ewerling, Alexander, Maissl, Vanessa, Wickstead, Bill, May-Simera, Helen Louise |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074162/ https://www.ncbi.nlm.nih.gov/pubmed/37034981 http://dx.doi.org/10.1016/j.isci.2023.106410 |
Ejemplares similares
-
The actin-bundling protein Fascin-1 modulates ciliary signalling
por: Brücker, Lena, et al.
Publicado: (2023) -
Loss of Ciliary Gene Bbs8 Results in Physiological Defects in the Retinal Pigment Epithelium
por: Schneider, Sandra, et al.
Publicado: (2021) -
Behavioral Phenotyping of Bbs6 and Bbs8 Knockout Mice Reveals Major Alterations in Communication and Anxiety
por: Rödig, Nathalie, et al.
Publicado: (2022) -
Dyneins Across Eukaryotes: A Comparative Genomic Analysis
por: Wickstead, Bill, et al.
Publicado: (2007) -
Translational readthrough of ciliopathy genes BBS2 and ALMS1 restores protein, ciliogenesis and function in patient fibroblasts
por: Eintracht, Jonathan, et al.
Publicado: (2021)