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Targeted DNA demethylation of the Arabidopsis genome using the SunTag-dCpf1-TET1cd system
DNA methylation is a stable and heritable epigenetic mark, and it plays an important role in regulation of gene expression and transposon silencing. Here we developed a CRISPR/dCpf1-based targeted demethylation system using the catalytic domain of the human demethylase TEN-ELEVEN TRANSLOCATION1 (TET...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Caltech Library
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074173/ https://www.ncbi.nlm.nih.gov/pubmed/37033707 http://dx.doi.org/10.17912/micropub.biology.000814 |