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Limited induction of polyfunctional lung-resident memory T cells against SARS-CoV-2 by mRNA vaccination compared to infection

Resident memory T cells (T(RM)) present at the respiratory tract may be essential to enhance early SARS-CoV-2 viral clearance, thus limiting viral infection and disease. While long-term antigen-specific T(RM) are detectable beyond 11 months in the lung of convalescent COVID-19 patients, it is unknow...

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Detalles Bibliográficos
Autores principales: Pieren, Daan K. J., Kuguel, Sebastián G., Rosado, Joel, Robles, Alba G., Rey-Cano, Joan, Mancebo, Cristina, Esperalba, Juliana, Falcó, Vicenç, Buzón, María J., Genescà, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074357/
https://www.ncbi.nlm.nih.gov/pubmed/37019909
http://dx.doi.org/10.1038/s41467-023-37559-w