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Computational Prodrug Design Methodology for Liposome Formulability Enhancement of Small-Molecule APIs

[Image: see text] Encapsulation into liposomes is a formulation strategy that can improve efficacy and reduce side effects of active pharmaceutical ingredients (APIs) that exhibit poor biodistribution or pharmacokinetics when administered alone. However, many APIs are unsuitable for liposomal formul...

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Detalles Bibliográficos
Autores principales: Balouch, Martin, Storchmannová, Kateřina, Štěpánek, František, Berka, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074381/
https://www.ncbi.nlm.nih.gov/pubmed/36939094
http://dx.doi.org/10.1021/acs.molpharmaceut.2c01078