Quantitative Imaging of Hypoxic CAIX-Positive Tumor Areas with Low Immune Cell Infiltration in Syngeneic Mouse Tumor Models

[Image: see text] Limited diffusion of oxygen in combination with increased oxygen consumption leads to chronic hypoxia in most solid malignancies. This scarcity of oxygen is known to induce radioresistance and leads to an immunosuppressive microenvironment. Carbonic anhydrase IX (CAIX) is an enzyme...

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Detalles Bibliográficos
Autores principales: Boreel, Daan F., Span, Paul N., Kip, Annemarie, Boswinkel, Milou, Peters, Johannes P. W., Adema, Gosse J., Bussink, Johan, Heskamp, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074386/
https://www.ncbi.nlm.nih.gov/pubmed/36882391
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074386/
https://www.ncbi.nlm.nih.gov/pubmed/36882391
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00045

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