Amides as modifiable directing groups in electrophilic borylation

Amide directed C–H borylation using ≥two equiv. of BBr(3) forms borenium cations containing a R(2)N(R′)C[double bond, length as m-dash]O→B(Ar)Br unit which has significant Lewis acidity at the carbonyl carbon. This enables reduction of the amide unit to an amine using hydrosilanes. This approach can...

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Detalles Bibliográficos
Autores principales: Iqbal, Saqib A., Uzelac, Marina, Nawaz, Ismat, Wang, Zhongxing, Jones, T. Harri, Yuan, Kang, Millet, Clement R. P., Nichol, Gary S., Chotana, Ghayoor Abbas, Ingleson, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074396/
https://www.ncbi.nlm.nih.gov/pubmed/37035693
http://dx.doi.org/10.1039/d2sc06483a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074396/
https://www.ncbi.nlm.nih.gov/pubmed/37035693
http://dx.doi.org/10.1039/d2sc06483a

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