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Amides as modifiable directing groups in electrophilic borylation
Amide directed C–H borylation using ≥two equiv. of BBr(3) forms borenium cations containing a R(2)N(R′)C[double bond, length as m-dash]O→B(Ar)Br unit which has significant Lewis acidity at the carbonyl carbon. This enables reduction of the amide unit to an amine using hydrosilanes. This approach can...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074396/ https://www.ncbi.nlm.nih.gov/pubmed/37035693 http://dx.doi.org/10.1039/d2sc06483a |