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Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform

Pleuromutilin is an antibiotic diterpenoid made by Clitopilus passeckerianus and related fungi, and it is the progenitor of a growing class of semi-synthetic antibiotics used in veterinary and human medicine. To harness the biotechnological potential of this natural product class, a full understandi...

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Detalles Bibliográficos
Autores principales: Alberti, Fabrizio, Khairudin, Khairunisa, Davies, Jonathan A., Sangmalee, Suphattra, Willis, Christine L., Foster, Gary D., Bailey, Andy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074412/
https://www.ncbi.nlm.nih.gov/pubmed/37035691
http://dx.doi.org/10.1039/d2sc06638f