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Semisynthesis reveals apoptin as a tumour-selective protein prodrug that causes cytoskeletal collapse
Apoptin is a small viral protein capable of inducing cell death selectively in cancer cells. Despite its potential as an anticancer agent, relatively little is known about its mechanism of toxicity and cancer-selectivity. Previous experiments suggest that cancer-selective phosphorylation modulates a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074440/ https://www.ncbi.nlm.nih.gov/pubmed/37035694 http://dx.doi.org/10.1039/d2sc04481a |