CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells

Newly generated immature B cells that bind self-antigen with high avidity arrest in differentiation and undergo central tolerance via receptor editing and clonal deletion. These autoreactive immature B cells also express low surface levels of the coreceptor CD19, a key activator of the PI3K pathway....

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Detalles Bibliográficos
Autores principales: McCaleb, Megan R., Miranda, Anjelica M., Ratliff, Kaysie C., Torres, Raul M., Pelanda, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Adaptive Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074640/
https://www.ncbi.nlm.nih.gov/pubmed/36637517
http://dx.doi.org/10.4049/immunohorizons.2200092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074640/
https://www.ncbi.nlm.nih.gov/pubmed/36637517
http://dx.doi.org/10.4049/immunohorizons.2200092

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