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Paired protein kinases PRKCI-RIPK2 promote pancreatic cancer growth and metastasis via enhancing NF-κB/JNK/ERK phosphorylation

BACKGROUND: Protein kinases play a pivotal role in the malignant evolution of pancreatic cancer (PC) through mediating phosphorylation. Many kinase inhibitors have been developed and translated into clinical use, while the complex pathology of PC confounds their clinical efficacy and warrants the di...

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Detalles Bibliográficos
Autores principales: Jiao, Juying, Ruan, Linjie, Cheng, Chien-shan, Wang, Fengjiao, Yang, Peiwen, Chen, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074657/
https://www.ncbi.nlm.nih.gov/pubmed/37016317
http://dx.doi.org/10.1186/s10020-023-00648-z