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COVID-19 therapeutics: Small-molecule drug development targeting SARS-CoV-2 main protease

The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is the causative factor behind the 2019 global coronavirus pandemic (COVID-19). The main protease, known as M(pro), is encoded by the viral genome and is essential for viral replication. It has also been an effective target for drug de...

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Detalles Bibliográficos
Autores principales: Kronenberger, Thales, Laufer, Stefan A., Pillaiyar, Thanigaimalai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074736/
https://www.ncbi.nlm.nih.gov/pubmed/37028502
http://dx.doi.org/10.1016/j.drudis.2023.103579