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Co-expression and clinical utility of AR-FL and AR splice variants AR-V3, AR-V7 and AR-V9 in prostate cancer

BACKGROUND: Androgen receptor (AR) splice variants (AR-Vs) have been discussed as a biomarker in prostate cancer (PC). However, some reports question the predictive property of AR-Vs. From a mechanistic perspective, the connection between AR full length (AR-FL) and AR-Vs is not fully understood. Her...

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Detalles Bibliográficos
Autores principales: Wüstmann, Neele, Seitzer, Konstantin, Humberg, Verena, Vieler, Julia, Grundmann, Norbert, Steinestel, Julie, Tiedje, Dorothee, Duensing, Stefan, Krabbe, Laura-Maria, Bögemann, Martin, Schrader, Andres Jan, Bernemann, Christof, Schlack, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074820/
https://www.ncbi.nlm.nih.gov/pubmed/37016463
http://dx.doi.org/10.1186/s40364-023-00481-w