ICOR: improving codon optimization with recurrent neural networks

BACKGROUND: In protein sequences—as there are 61 sense codons but only 20 standard amino acids—most amino acids are encoded by more than one codon. Although such synonymous codons do not alter the encoded amino acid sequence, their selection can dramatically affect the expression of the resulting pr...

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Detalles Bibliográficos
Autores principales: Jain, Rishab, Jain, Aditya, Mauro, Elizabeth, LeShane, Kevin, Densmore, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074884/
https://www.ncbi.nlm.nih.gov/pubmed/37016283
http://dx.doi.org/10.1186/s12859-023-05246-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074884/
https://www.ncbi.nlm.nih.gov/pubmed/37016283
http://dx.doi.org/10.1186/s12859-023-05246-8

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