Cargando…
ICOR: improving codon optimization with recurrent neural networks
BACKGROUND: In protein sequences—as there are 61 sense codons but only 20 standard amino acids—most amino acids are encoded by more than one codon. Although such synonymous codons do not alter the encoded amino acid sequence, their selection can dramatically affect the expression of the resulting pr...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074884/ https://www.ncbi.nlm.nih.gov/pubmed/37016283 http://dx.doi.org/10.1186/s12859-023-05246-8 |