Dihydroartemisinin-piperaquine or sulphadoxine-pyrimethamine for the chemoprevention of malaria in children with sickle cell anaemia in eastern and southern Africa (CHEMCHA): a protocol for a multi-centre, two-arm, double-blind, randomised, placebo-controlled superiority trial

BACKGROUND: An estimated 300,000 babies are born with sickle cell anaemia (SCA) annually. Affected children have chronic ill health and suffer premature death. Febrile illnesses such as malaria commonly precipitate acute crises in children with SCA. Thus, chemoprophylaxis for malaria is an important...

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Detalles Bibliográficos
Autores principales: Nkosi-Gondwe, Thandile, Robberstad, Bjarne, Opoka, Robert, Kalibbala, Dennis, Rujumba, Joseph, Galileya, Lufina Tsirizani, Akun, Pamela, Nambatya, Winnie, Ssenkusu, John, TerKuile, Feiko, Phiri, Kamija, Idro, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074896/
https://www.ncbi.nlm.nih.gov/pubmed/37016392
http://dx.doi.org/10.1186/s13063-023-07274-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074896/
https://www.ncbi.nlm.nih.gov/pubmed/37016392
http://dx.doi.org/10.1186/s13063-023-07274-4

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