Cargando…

Dihydroartemisinin-piperaquine or sulphadoxine-pyrimethamine for the chemoprevention of malaria in children with sickle cell anaemia in eastern and southern Africa (CHEMCHA): a protocol for a multi-centre, two-arm, double-blind, randomised, placebo-controlled superiority trial

BACKGROUND: An estimated 300,000 babies are born with sickle cell anaemia (SCA) annually. Affected children have chronic ill health and suffer premature death. Febrile illnesses such as malaria commonly precipitate acute crises in children with SCA. Thus, chemoprophylaxis for malaria is an important...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nkosi-Gondwe, Thandile, Robberstad, Bjarne, Opoka, Robert, Kalibbala, Dennis, Rujumba, Joseph, Galileya, Lufina Tsirizani, Akun, Pamela, Nambatya, Winnie, Ssenkusu, John, TerKuile, Feiko, Phiri, Kamija, Idro, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074896/ https://www.ncbi.nlm.nih.gov/pubmed/37016392 http://dx.doi.org/10.1186/s13063-023-07274-4

Ejemplares similares

Adherence to community versus facility-based delivery of monthly malaria chemoprevention with dihydroartemisinin-piperaquine for the post-discharge management of severe anemia in Malawian children: A cluster randomized trial
por: Nkosi-Gondwe, Thandile, et al.
Publicado: (2021)

Economic evaluation of postdischarge malaria chemoprevention in preschool children treated for severe anaemia in Malawi, Kenya, and Uganda: A cost-effectiveness analysis
por: Kühl, Melf-Jakob, et al.
Publicado: (2022)

Predicting adherence to postdischarge malaria chemoprevention in Malawian pre-school children: A prognostic multivariable analysis
por: Kühl, Melf-Jakob, et al.
Publicado: (2023)

Delivery strategies for malaria chemoprevention with monthly dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years old in Malawi: a protocol for a cluster randomized trial
por: Gondwe, Thandile, et al.
Publicado: (2018)

Introducing post-discharge malaria chemoprevention (PMC) for management of severe anemia in Malawian children: a qualitative study of community health workers’ perceptions and motivation
por: Nkosi-Gondwe, Thandile, et al.
Publicado: (2018)

Post-discharge malaria chemoprevention (PMC) in Malawi: caregivers` acceptance and preferences with regard to delivery methods
por: Svege, Sarah, et al.
Publicado: (2018)

Malaria chemoprevention with monthly dihydroartemisinin-piperaquine for the post-discharge management of severe anaemia in children aged less than 5 years in Uganda and Kenya: study protocol for a multi-centre, two-arm, randomised, placebo-controlled, superiority trial
por: Kwambai, Titus K., et al.
Publicado: (2018)

Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa
por: Okell, Lucy C., et al.
Publicado: (2023)

Impact of Dolutegravir-Based Antiretroviral Therapy on Piperaquine Exposure following Dihydroartemisinin-Piperaquine Intermittent Preventive Treatment of Malaria in Pregnant Women Living with HIV
por: Banda, Clifford G., et al.
Publicado: (2022)

Dihydroartemisinin–piperaquine holds promise as an option for malaria prevention in pregnancy
por: Hill, Jenny, et al.
Publicado: (2016)

Efficacy of sulphadoxine-pyrimethamine + artesunate, sulphadoxine-pyrimethamine + amodiaquine, and sulphadoxine-pyrimethamine alone in uncomplicated falciparum malaria in Mali
por: Maiga, Hamma, et al.
Publicado: (2015)

Estimated impact on birth weight of scaling up intermittent preventive treatment of malaria in pregnancy given sulphadoxine-pyrimethamine resistance in Africa: A mathematical model
por: Walker, Patrick G. T., et al.
Publicado: (2017)

Effect of dihydroartemisinin/piperaquine for malaria intermittent preventive treatment on dolutegravir exposure in pregnant women living with HIV
por: Banda, Clifford G., et al.
Publicado: (2022)

A cohort analysis of survival and outcomes in severely anaemic children with moderate to severe acute malnutrition in Malawi
por: Nkosi-Gondwe, Thandile, et al.
Publicado: (2021)

“Satanism is witchcraft’s younger sibling”: Changing perceptions of natural and supernatural anaemia causality in Malawian children
por: Svege, Sarah, et al.
Publicado: (2021)

Safety, tolerability, and efficacy of repeated doses of dihydroartemisinin-piperaquine for prevention and treatment of malaria: a systematic review and meta-analysis
por: Gutman, Julie, et al.
Publicado: (2017)

Efficacy of Artesunate + Sulphadoxine-Pyrimethamine (AS + SP) and Amodiaquine + Sulphadoxine-Pyrimethamine (AQ + SP) for Uncomplicated falciparum Malaria in Equatorial Guinea (Central Africa)
por: Charle, Pilar, et al.
Publicado: (2009)

Intermittent screening and treatment with dihydroartemisinin-piperaquine and intermittent preventive therapy with sulfadoxine-pyrimethamine have similar effects on malaria antibody in pregnant Malawian women
por: Teo, Andrew, et al.
Publicado: (2019)

Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya
por: Iriemenam, Nnaemeka C, et al.
Publicado: (2012)

Parasite clearance following treatment with sulphadoxine-pyrimethamine for intermittent preventive treatment in Burkina-Faso and Mali: 42-day in vivo follow-up study
por: Coulibaly, Sheick O, et al.
Publicado: (2014)

Proportions of CD4+, CD8+ and B cell subsets are not affected by exposure to HIV or to Cotrimoxazole prophylaxis in Malawian HIV-uninfected but exposed children
por: Longwe, Herbert, et al.
Publicado: (2015)

Delayed acquisition of Plasmodium falciparum antigen-specific CD4(+) T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis
por: Longwe, Herbert, et al.
Publicado: (2016)

Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy
por: Gutman, Julie, et al.
Publicado: (2012)

Declining efficacy of artesunate plus sulphadoxine-pyrimethamine in northeastern India
por: Mishra, Neelima, et al.
Publicado: (2014)

Isoniazid preventive therapy-related adverse events among Malawian adults on antiretroviral therapy: A cohort study
por: Tsirizani-Galileya, Lufina, et al.
Publicado: (2022)

Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy
por: Chotsiri, Palang, et al.
Publicado: (2021)

Budget Impact Analysis of Using Dihydroartemisinin–Piperaquine to Treat Uncomplicated Malaria in Children in Tanzania
por: Mori, Amani Thomas, et al.
Publicado: (2015)

Drug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, Tanzania
por: Mbugi, Erasto V, et al.
Publicado: (2006)

Inequities in the use of sulphadoxine-pyrimethamine for malaria prophylaxis during pregnancy in Nigeria
por: Ndu, Anne, et al.
Publicado: (2020)

Intermittent screening and treatment with artemisinin-combination therapy versus intermittent preventive treatment with sulphadoxine-pyrimethamine for malaria in pregnancy: a systematic review and individual participant data meta-analysis of randomised clinical trials
por: Gutman, Julie R, et al.
Publicado: (2021)

Efficacy of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy, Mansa, Zambia
por: Tan, Kathrine R, et al.
Publicado: (2014)

Effectiveness of intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) in Ghana
por: Dosoo, David Kwame, et al.
Publicado: (2021)

Effectiveness of antenatal intermittent preventive treatment for malaria with sulphadoxine-pyrimethamine on peripartum outcomes
por: Godwin, Isaac Okezie, et al.
Publicado: (2022)

Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis
por: Galileya, Lufina Tsirizani, et al.
Publicado: (2023)

Effect of monthly intermittent preventive treatment with dihydroartemisinin–piperaquine with and without azithromycin versus monthly sulfadoxine–pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial
por: Madanitsa, Mwayiwawo, et al.
Publicado: (2023)

Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Trial
por: Madanitsa, Mwayiwawo, et al.
Publicado: (2016)

Compensation of subjects for participation in biomedical research in resource – limited settings: a discussion of practices in Malawi
por: Nyangulu, Wongani, et al.
Publicado: (2019)

Cost-effectiveness of intermittent preventive treatment with dihydroartemisinin–piperaquine for malaria during pregnancy: an analysis using efficacy results from Uganda and Kenya, and pooled data
por: Fernandes, Silke, et al.
Publicado: (2020)

Therapeutic efficacy of sulphadoxine-pyrimethamine and chloroquine for the treatment of uncomplicated malaria in pregnancy in Burkina Faso
por: Coulibaly, Sheick Oumar, et al.
Publicado: (2006)

Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area
por: Gama, Bianca Ervatti, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_c7p0p3lumrlgqhf60nheubk6h0