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N(ε)-(carboxymethyl)lysine promotes lipid uptake of macrophage via cluster of differentiation 36 and receptor for advanced glycation end products

BACKGROUND: Advanced glycation end products (AGEs) are diabetic metabolic toxic products that cannot be ignored. N(ε)-(carboxymethyl)lysine (CML), a component of AGEs, could increase macrophage lipid uptake, promote foam cell formation, and thereby accelerate atherosclerosis. The receptor for AGEs (...

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Detalles Bibliográficos
Autores principales: Wang, Zhong-Qun, Yao, Hai-Peng, Sun, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075039/
https://www.ncbi.nlm.nih.gov/pubmed/37035231
http://dx.doi.org/10.4239/wjd.v14.i3.222