Oncogenic BRAF(V600E) induces microglial proliferation through extracellular signal-regulated kinase and neuronal death through c-Jun N-terminal kinase

Activating V600E in v-Raf murine sarcoma viral oncogene homolog B (BRAF) is a common driver mutation in cancers of multiple tissue origins, including melanoma and glioma. BRAF(V600E) has also been implicated in neurodegeneration. The present study aims to characterize BRAF(V600E) during cell death a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Qing, Srivastava, Pranay, Al-Kuwari, Nasser, Chen, Xiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075110/
https://www.ncbi.nlm.nih.gov/pubmed/36571370
http://dx.doi.org/10.4103/1673-5374.361516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075110/
https://www.ncbi.nlm.nih.gov/pubmed/36571370
http://dx.doi.org/10.4103/1673-5374.361516

Ejemplares similares