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Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway

Treatment with metformin can lead to the recovery of pleiotropic biological activities after spinal cord injury. However, its effect on spinal cord injury in aged mice remains unclear. Considering the essential role of angiogenesis during the regeneration process, we hypothesized that metformin acti...

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Detalles Bibliográficos
Autores principales: Zhao, Jin-Yun, Sheng, Xiao-Long, Li, Cheng-Jun, Qin, Tian, He, Run-Dong, Dai, Guo-Yu, Cao, Yong, Lu, Hong-Bin, Duan, Chun-Yue, Hu, Jian-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075126/
https://www.ncbi.nlm.nih.gov/pubmed/36571362
http://dx.doi.org/10.4103/1673-5374.360245