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Valproate reduces retinal ganglion cell apoptosis in rats after optic nerve crush

The retinal ganglion cells of the optic nerve have a limited capacity for self-repair after injury. Valproate is a histone deacetylase inhibitor and multitarget drug, which has been demonstrated to protect retinal neurons. In this study, we established rat models of optic nerve-crush injury and inje...

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Detalles Bibliográficos
Autores principales: Pan, Feng, Hu, Dan, Sun, Li-Juan, Bai, Qian, Wang, Yu-Sheng, Hou, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075129/
https://www.ncbi.nlm.nih.gov/pubmed/36571369
http://dx.doi.org/10.4103/1673-5374.357913