Hydrogel armed with Bmp2 mRNA-enriched exosomes enhances bone regeneration

BACKGROUND: Sustained release of bioactive BMP2 (bone morphogenetic protein-2) is important for bone regeneration, while the intrinsic short half-life of BMP2 at protein level cannot meet the clinical need. In this study, we aimed to design Bmp2 mRNA-enriched engineered exosomes, which were then loa...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zhujun, Li, Xuejian, Gan, Xueqi, Wei, Mengying, Wang, Chunbao, Yang, Guodong, Zhao, Yimin, Zhu, Zhuoli, Wang, Zhongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075167/
https://www.ncbi.nlm.nih.gov/pubmed/37020301
http://dx.doi.org/10.1186/s12951-023-01871-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075167/
https://www.ncbi.nlm.nih.gov/pubmed/37020301
http://dx.doi.org/10.1186/s12951-023-01871-w

Ejemplares similares