Cargando…
Hydrogel armed with Bmp2 mRNA-enriched exosomes enhances bone regeneration
BACKGROUND: Sustained release of bioactive BMP2 (bone morphogenetic protein-2) is important for bone regeneration, while the intrinsic short half-life of BMP2 at protein level cannot meet the clinical need. In this study, we aimed to design Bmp2 mRNA-enriched engineered exosomes, which were then loa...
Autores principales: | Yang, Zhujun, Li, Xuejian, Gan, Xueqi, Wei, Mengying, Wang, Chunbao, Yang, Guodong, Zhao, Yimin, Zhu, Zhuoli, Wang, Zhongshan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075167/ https://www.ncbi.nlm.nih.gov/pubmed/37020301 http://dx.doi.org/10.1186/s12951-023-01871-w |
Ejemplares similares
-
ROS triggered local delivery of stealth exosomes to tumors for enhanced chemo/photodynamic therapy
por: Wan, Zhuo, et al.
Publicado: (2022) -
Chitosan/Hyaluronic Acid/MicroRNA-21 Nanoparticle-Coated Smooth Titanium Surfaces Promote the Functionality of Human Gingival Fibroblasts
por: Wang, Zhongshan, et al.
Publicado: (2022) -
Recapitulation of growth factor-enriched microenvironment via BMP receptor activating hydrogel
por: Zhang, Qinghao, et al.
Publicado: (2022) -
Exosome-bearing hydrogels and cardiac tissue regeneration
por: Amini, Hassan, et al.
Publicado: (2023) -
Injectable hydrogel with immobilized BMP-2 mimetic peptide for local bone regeneration
por: Gultian, Kirstene A., et al.
Publicado: (2022)