RNA recruitment switches the fate of protein condensates from autophagic degradation to accumulation

Protein condensates can evade autophagic degradation under stress or pathological conditions. However, the underlying mechanisms are unclear. Here, we demonstrate that RNAs switch the fate of condensates in Caenorhabditis elegans. PGL granules undergo autophagic degradation in embryos laid under nor...

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Detalles Bibliográficos
Autores principales: Zheng, Hui, Peng, Kangfu, Gou, Xiaomeng, Ju, Chen, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075224/
https://www.ncbi.nlm.nih.gov/pubmed/37014300
http://dx.doi.org/10.1083/jcb.202210104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075224/
https://www.ncbi.nlm.nih.gov/pubmed/37014300
http://dx.doi.org/10.1083/jcb.202210104

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