Cargando…

Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals

Adaptive immunity’s success relies on the extraordinary diversity of protein receptors on B and T cell membranes. Despite this diversity, the existence of public receptors shared by many individuals gives hope for developing population-wide vaccines and therapeutics. Using probabilistic modeling, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruiz Ortega, María, Spisak, Natanael, Mora, Thierry, Walczak, Aleksandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075420/
https://www.ncbi.nlm.nih.gov/pubmed/36827454
http://dx.doi.org/10.1371/journal.pgen.1010652