A novel integrative multi-omics approach to unravel the genetic determinants of rare diseases with application in sinusoidal obstruction syndrome

BACKGROUND: Genotype-phenotype analyses of rare diseases often suffer from a lack of power, due to small sample size, which makes identifying significant associations difficult. Sinusoidal obstruction syndrome (SOS) of the liver is a rare but life-threatening complication of hematopoietic stem cell...

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Detalles Bibliográficos
Autores principales: Waespe, Nicolas, Mlakar, Simona Jurkovic, Dupanloup, Isabelle, Rezgui, Mohamed Aziz, Bittencourt, Henrique, Krajinovic, Maja, Kuehni, Claudia E., Nava, Tiago, Ansari, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075428/
https://www.ncbi.nlm.nih.gov/pubmed/37018234
http://dx.doi.org/10.1371/journal.pone.0281892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075428/
https://www.ncbi.nlm.nih.gov/pubmed/37018234
http://dx.doi.org/10.1371/journal.pone.0281892

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