Determination of adenosine by CRISPR-Cas12a system based on duplexed aptamer and molecular beacon reporter linked to gold nanoparticles

Adenosine as a potential tumor marker is of great value for clinical disease diagnosis. Since the CRISPR-cas12a system is only capable of recognizing nucleic acid targets we expanded the CRISPR-cas12a system to determine small molecules by designing a duplexed aptamer (DA) converting g-RNA recogniti...

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Detalles Bibliográficos
Autores principales: Liu, Zhenhua, Quan, Lingling, Ma, Fanghui, Yang, Minghui, Jiang, Xinyu, Chen, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075494/
https://www.ncbi.nlm.nih.gov/pubmed/37020072
http://dx.doi.org/10.1007/s00604-023-05748-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075494/
https://www.ncbi.nlm.nih.gov/pubmed/37020072
http://dx.doi.org/10.1007/s00604-023-05748-5

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