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Lesional Antibody Synthesis and Complement Deposition Associate With De Novo Antineuronal Antibody Synthesis After Spinal Cord Injury

BACKGROUND AND OBJECTIVES: Spinal cord injury (SCI) disrupts the fine-balanced interaction between the CNS and immune system and can cause maladaptive aberrant immune responses. The study examines emerging autoantibody synthesis after SCI with binding to conformational spinal cord epitopes and surfa...

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Detalles Bibliográficos
Autores principales: Schwab, Jan M., Haider, Carmen, Kopp, Marcel A., Zrzavy, Tobias, Endmayr, Verena, Ricken, Gerda, Kubista, Helmut, Haider, Thomas, Liebscher, Thomas, Lübstorf, Tom, Blex, Christian, Serdani-Neuhaus, Leonarda, Curt, Armin, Cinelli, Paolo, Scivoletto, Giorgio, Fehlings, Michael G., May, Caroline, Guntermann, Annika, Marcus, Katrin, Meisel, Christian, Dirnagl, Ulrich, Martus, Peter, Prüss, Harald, Popovich, Phillip G., Lassmann, Hans, Höftberger, Romana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075523/
https://www.ncbi.nlm.nih.gov/pubmed/37019668
http://dx.doi.org/10.1212/NXI.0000000000200099