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Identification of 113 new histone marks by CHiMA, a tailored database search strategy
Shotgun proteomics has been widely used to identify histone marks. Conventional database search methods rely on the “target-decoy” strategy to calculate the false discovery rate (FDR) and distinguish true peptide-spectrum matches (PSMs) from false ones. This strategy has a caveat of inaccurate FDR c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075957/ https://www.ncbi.nlm.nih.gov/pubmed/37018393 http://dx.doi.org/10.1126/sciadv.adf1416 |