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Identification of 113 new histone marks by CHiMA, a tailored database search strategy

Shotgun proteomics has been widely used to identify histone marks. Conventional database search methods rely on the “target-decoy” strategy to calculate the false discovery rate (FDR) and distinguish true peptide-spectrum matches (PSMs) from false ones. This strategy has a caveat of inaccurate FDR c...

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Detalles Bibliográficos
Autores principales:	Gao, Jinjun, Sheng, Xinlei, Du, Jianfeng, Zhang, Di, Han, Chang, Chen, Yue, Wang, Chu, Zhao, Yingming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075957/ https://www.ncbi.nlm.nih.gov/pubmed/37018393 http://dx.doi.org/10.1126/sciadv.adf1416

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