An IL-6/STAT3/MR/FGF21 axis mediates heart-liver cross-talk after myocardial infarction

The liver plays a protective role in myocardial infarction (MI). However, very little is known about the mechanisms. Here, we identify mineralocorticoid receptor (MR) as a pivotal nexus that conveys communications between the liver and the heart during MI. Hepatocyte MR deficiency and MR antagonist...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jian-Yong, Du, Lin-Juan, Shi, Xue-Rui, Zhang, Yu-Yao, Liu, Yuan, Wang, Yong-Li, Chen, Bo-Yan, Liu, Ting, Zhu, Hong, Liu, Yan, Ruan, Cheng-Chao, Gan, Zhenji, Ying, Hao, Yin, Zhinan, Gao, Ping-Jin, Yan, Xiaoxiang, Li, Ruo-Gu, Duan, Sheng-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075967/
https://www.ncbi.nlm.nih.gov/pubmed/37018396
http://dx.doi.org/10.1126/sciadv.ade4110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075967/
https://www.ncbi.nlm.nih.gov/pubmed/37018396
http://dx.doi.org/10.1126/sciadv.ade4110

Ejemplares similares