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An IL-6/STAT3/MR/FGF21 axis mediates heart-liver cross-talk after myocardial infarction

The liver plays a protective role in myocardial infarction (MI). However, very little is known about the mechanisms. Here, we identify mineralocorticoid receptor (MR) as a pivotal nexus that conveys communications between the liver and the heart during MI. Hepatocyte MR deficiency and MR antagonist...

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Detalles Bibliográficos
Autores principales:	Sun, Jian-Yong, Du, Lin-Juan, Shi, Xue-Rui, Zhang, Yu-Yao, Liu, Yuan, Wang, Yong-Li, Chen, Bo-Yan, Liu, Ting, Zhu, Hong, Liu, Yan, Ruan, Cheng-Chao, Gan, Zhenji, Ying, Hao, Yin, Zhinan, Gao, Ping-Jin, Yan, Xiaoxiang, Li, Ruo-Gu, Duan, Sheng-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075967/ https://www.ncbi.nlm.nih.gov/pubmed/37018396 http://dx.doi.org/10.1126/sciadv.ade4110

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