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Lipid hydroperoxides promote sarcopenia through carbonyl stress

Reactive oxygen species (ROS) accumulation is a cardinal feature of skeletal muscle atrophy. ROS refers to a collection of radical molecules whose cellular signals are vast, and it is unclear which downstream consequences of ROS are responsible for the loss of muscle mass and strength. Here, we show...

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Detalles Bibliográficos
Autores principales: Eshima, Hiroaki, Shahtout, Justin L, Siripoksup, Piyarat, Pearson, MacKenzie J, Mahmassani, Ziad S, Ferrara, Patrick J, Lyons, Alexis W, Maschek, John Alan, Peterlin, Alek D, Verkerke, Anthony RP, Johnson, Jordan M, Salcedo, Anahy, Petrocelli, Jonathan J, Miranda, Edwin R, Anderson, Ethan J, Boudina, Sihem, Ran, Qitao, Cox, James E, Drummond, Micah J, Funai, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076018/
https://www.ncbi.nlm.nih.gov/pubmed/36951533
http://dx.doi.org/10.7554/eLife.85289