Efficient Modulation of Exon Skipping via Antisense Circular RNAs

Splice-switching antisense oligonucleotides (ASOs) and engineered U7 small nuclear ribonucleoprotein (U7 Sm OPT) are the most commonly used methods for exon skipping. However, challenges remain, such as limited organ delivery and repeated dosing for ASOs and unknown risks of by-products produced by...

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Detalles Bibliográficos
Autores principales: Ren, Shuaiwei, Huang, Mei, Bai, Raoxian, Chen, Lijiao, Yang, Jiao, Zhang, Junyu, Guo, Wenting, Ji, Weizhi, Chen, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076032/
https://www.ncbi.nlm.nih.gov/pubmed/37040525
http://dx.doi.org/10.34133/research.0045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076032/
https://www.ncbi.nlm.nih.gov/pubmed/37040525
http://dx.doi.org/10.34133/research.0045

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