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The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment

Aortic valves (AVs) undergo unique stretch histories that include high rates and magnitudes. While major differences in deformation patterns have been observed between normal and congenitally defective bicuspid aortic valves (BAVs), the relation to underlying mechanisms of rapid disease onset in BAV...

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Detalles Bibliográficos
Autores principales: West, Toni M., Howsmon, Daniel P., Massidda, Miles W., Vo, Helen N., Janobas, Athena A., Baker, Aaron B., Sacks, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076067/
https://www.ncbi.nlm.nih.gov/pubmed/37035541
http://dx.doi.org/10.1063/5.0138030