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The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment
Aortic valves (AVs) undergo unique stretch histories that include high rates and magnitudes. While major differences in deformation patterns have been observed between normal and congenitally defective bicuspid aortic valves (BAVs), the relation to underlying mechanisms of rapid disease onset in BAV...
Autores principales: | West, Toni M., Howsmon, Daniel P., Massidda, Miles W., Vo, Helen N., Janobas, Athena A., Baker, Aaron B., Sacks, Michael S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076067/ https://www.ncbi.nlm.nih.gov/pubmed/37035541 http://dx.doi.org/10.1063/5.0138030 |
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