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Dihydrocaffeic acid improves IL-1β-induced inflammation and cartilage degradation via inhibiting NF-κB and MAPK signalling pathways

AIMS: Osteoarthritis (OA) is a prevalent joint disorder with inflammatory response and cartilage deterioration as its main features. Dihydrocaffeic acid (DHCA), a bioactive component extracted from natural plant (gynura bicolor), has demonstrated anti-inflammatory properties in various diseases. We...

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Detalles Bibliográficos
Autores principales: Lu, Rui, Wang, Ying-Guang, Qu, Yunkun, Wang, Shan-Xi, Peng, Cheng, You, Hongbo, Zhu, Wentao, Chen, Anmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076109/
https://www.ncbi.nlm.nih.gov/pubmed/37492935
http://dx.doi.org/10.1302/2046-3758.124.BJR-2022-0384.R1