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Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease

Coronavirus Papain-like protease (PLpro) mediates the cleavage of viral polyproteins and assists the virus escaping from innate immune response. Thus, PLpro is an attractive target for the development of broad-spectrum drugs as it has a conserved structure across different coronaviruses. In this stu...

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Detalles Bibliográficos
Autores principales: Qiao, Huarui, Li, Lingyun, Wang, Lu, Yu, Haijun, Hu, Fangzheng, Zhou, Xin, Yang, Hongzhao, Xu, Jianfeng, Meng, Xiangjing, Geng, Yong, Dai, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076250/
https://www.ncbi.nlm.nih.gov/pubmed/37030644
http://dx.doi.org/10.1016/j.pep.2023.106267