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The m(6)A reader YTHDC1 and the RNA helicase DDX5 control the production of rhabdomyosarcoma-enriched circRNAs

N6-Methyladenosine (m(6)A) is well-known for controlling different processes of linear RNA metabolism. Conversely, its role in the biogenesis and function of circular RNAs (circRNAs) is still poorly understood. Here, we characterize circRNA expression in the pathological context of rhabdomyosarcoma...

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Detalles Bibliográficos
Autores principales: Dattilo, Dario, Di Timoteo, Gaia, Setti, Adriano, Giuliani, Andrea, Peruzzi, Giovanna, Beltran Nebot, Manuel, Centrón-Broco, Alvaro, Mariani, Davide, Mozzetta, Chiara, Bozzoni, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076346/
https://www.ncbi.nlm.nih.gov/pubmed/37019933
http://dx.doi.org/10.1038/s41467-023-37578-7