Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are increasingly used for personalised medicine and preclinical cardiotoxicity testing. Reports on hiPSC-CM commonly describe heterogenous functional readouts and underdeveloped or immature phenotypical properties. Cost-effective...

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Detalles Bibliográficos
Autores principales: Seibertz, Fitzwilliam, Sutanto, Henry, Dülk, Rebekka, Pronto, Julius Ryan D., Springer, Robin, Rapedius, Markus, Liutkute, Aiste, Ritter, Melanie, Jung, Philipp, Stelzer, Lea, Hüsgen, Luisa M., Klopp, Marie, Rubio, Tony, Fakuade, Funsho E., Mason, Fleur E., Hartmann, Nico, Pabel, Steffen, Streckfuss-Bömeke, Katrin, Cyganek, Lukas, Sossalla, Samuel, Heijman, Jordi, Voigt, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076390/
https://www.ncbi.nlm.nih.gov/pubmed/37020075
http://dx.doi.org/10.1007/s00395-022-00973-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076390/
https://www.ncbi.nlm.nih.gov/pubmed/37020075
http://dx.doi.org/10.1007/s00395-022-00973-0

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