Enhanced axonal regeneration of ALS patient iPSC-derived motor neurons harboring SOD1(A4V) mutation

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, characterized by degeneration of upper and lower motor neurons that leads to muscle weakness, paralysis, and death, but the effects of disease-causing mutations on axonal outgrowth of neurons derived from human induced p...

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Detalles Bibliográficos
Autores principales: Marshall, Katherine L., Rajbhandari, Labchan, Venkatesan, Arun, Maragakis, Nicholas J., Farah, Mohamed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076424/
https://www.ncbi.nlm.nih.gov/pubmed/37020097
http://dx.doi.org/10.1038/s41598-023-31720-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076424/
https://www.ncbi.nlm.nih.gov/pubmed/37020097
http://dx.doi.org/10.1038/s41598-023-31720-7

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