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Enhanced axonal regeneration of ALS patient iPSC-derived motor neurons harboring SOD1(A4V) mutation
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, characterized by degeneration of upper and lower motor neurons that leads to muscle weakness, paralysis, and death, but the effects of disease-causing mutations on axonal outgrowth of neurons derived from human induced p...
Autores principales: | Marshall, Katherine L., Rajbhandari, Labchan, Venkatesan, Arun, Maragakis, Nicholas J., Farah, Mohamed H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076424/ https://www.ncbi.nlm.nih.gov/pubmed/37020097 http://dx.doi.org/10.1038/s41598-023-31720-7 |
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